Aug. 21st, 2021

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There's been some reporting recently of vaccines not protecting against severe infection as well as expected, based on looking at the number of hospitalized people who are vaccinated vs not. "60% of people with severe COVID-19 in the hospital had been vaccinated!" Here's an article explaining why this analysis is complete junk:

https://www.covid-datascience.com/post/israeli-data-how-can-efficacy-vs-severe-disease-be-strong-when-60-of-hospitalized-are-vaccinated

If you're familiar with Simpson's paradox, it's another case of that. TL;DR: Vaccination status is highly correlated with age, and if you actually slice up the cases by age, you see that efficacy against severe disease is 80–100%, depending on age. And yes, this is in the context of the Delta variant (or other current strains).

(But also see the article for some additional confounding factors.)

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